DRD3 antibody (AA 213-329)

Catalog No. ABIN3015510

This anti-DRD3 antibody is a Rabbit Polyclonal antibody detecting DRD3 in WB and IF. Suitable for Human.

Quick Overview for DRD3 antibody (AA 213-329) (ABIN3015510)

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-DRD3 Antibody

Binding Specificity: AA 213-329

Sequence: VVLKQRRRKR ILTRQNSQCN SVRPGFPQQT LSPDPAHLEL KRYYSICQDT ALGGPGFQER GGELKREEKT RNSLSPTIAP KLSLEVRKLS NGRLSTSLKL GPLQPRGVPL REKKATQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 213-329 of human Dopamine Receptor D3 (Dopamine Receptor D3 (DRD3)) (NP_000787.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Alternative Name: DRD3

Background: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).,DRD3,D3DR,ETM1,FET1,Neuroscience,DRD3

Molecular Weight: 40 kDa/44 kDa

Gene ID: 1814

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity