DRD4 antibody (AA 100-200)

Catalog No. ABIN1679595

This anti-DRD4 antibody is a Rabbit Polyclonal antibody detecting DRD4 in WB and IHC. Suitable for Human.

Quick Overview for DRD4 antibody (AA 100-200) (ABIN1679595)

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DRD4 Antibody

Binding Specificity: AA 100-200

Sequence: AWLLSPRLCD ALMAMDVMLC TASIFNLCAI SVDRFVAVAV PLRYNRQGGS RRQLLLIGAT WLLSAAVAAP VLCGLNDVRG RDPAVCRLED RDYVVYSSVC S

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRD4 (NP_000788.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DRD4

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Alternative Name: DRD4

Background: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats.,DRD4,D4DR,Neuroscience,DRD4

Molecular Weight: 48 kDa

Gene ID: 1815

UniProt: P21917

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity