MAPRE1 antibody (AA 134-268)

Catalog No. ABIN1679634

Product Details anti-MAPRE1 Antibody

Target: MAPRE1 (Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1))

Binding Specificity: AA 134-268

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPRE1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ETAVAPSLVA PALNKPKKPL TSSSAAPQRP ISTQRTAAAP KAGPGVVRKN PGVGNGDDEA AELMQQVNVL KLTVEDLEKE RDFYFGKLRN IELICQENEG ENDPVLQRIV DILYATDEGF VIPDEGGPQE EQEEY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 134-268 of human MAPRE1 (NP_036457.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAPRE1

Target: MAPRE1 (Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1))

Alternative Name: MAPRE1 (MAPRE1 Products)

Background: The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.,MAPRE1,EB1,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Microtubules,MAPRE1

Molecular Weight: 29 kDa

Gene ID: 22919

UniProt: Q15691

Pathways: M Phase