FGF12 antibody (AA 1-181)

Catalog No. ABIN1679841

The Rabbit Polyclonal anti-FGF12 antibody has been validated for WB, IHC and IF. It is suitable to detect FGF12 in samples from Human.

Quick Overview for FGF12 antibody (AA 1-181) (ABIN1679841)

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FGF12 Antibody

Binding Specificity: AA 1-181

Sequence: MESKEPQLKG IVTRLFSQQG YFLQMHPDGT IDGTKDENSD YTLFNLIPVG LRVVAIQGVK ASLYVAMNGE GYLYSSDVFT PECKFKESVF ENYYVIYSST LYRQQESGRA WFLGLNKEGQ IMKGNRVKKT KPSSHFVPKP IEVCMYREPS LHEIGEKQGR SRKSSGTPTM NGGKVVNQDS T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human FGF12 (NP_004104.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FGF12

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Alternative Name: FGF12

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.,FGF12,EIEE47,FGF12B,FHF1,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Cardiovascular,Angiogenesis,FGF12

Molecular Weight: 20 kDa/27 kDa

Gene ID: 2257

UniProt: P61328

Pathways: Negative Regulation of Transporter Activity