Plastin 3 antibody (AA 1-240)

Catalog No. ABIN1682206

This Rabbit Polyclonal antibody specifically detects Plastin 3 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Plastin 3 antibody (AA 1-240) (ABIN1682206)

Target: Plastin 3 (PLS3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plastin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Plastin 3 Antibody

Binding Specificity: AA 1-240

Sequence: MDEMATTQIS KDELDELKEA FAKVDLNSNG FICDYELHEL FKEANMPLPG YKVREIIQKL MLDGDRNKDG KISFDEFVYI FQEVKSSDIA KTFRKAINRK EGICALGGTS ELSSEGTQHS YSEEEKYAFV NWINKALEND PDCRHVIPMN PNTDDLFKAV GDGIVLCKMI NLSVPDTIDE RAINKKKLTP FIIQENLNLA LNSASAIGCH VVNIGAEDLR AGKPHLVLGL LWQIIKIGLF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PLS3 (NP_005023.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IP,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Plastin 3

Target: Plastin 3 (PLS3)

Alternative Name: PLS3

Background: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83 % identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.,PLS3,BMND18,T-plastin,plastin-3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Extracellular Matrix,PLS3

Molecular Weight: 65 kDa/69 kDa/70 kDa

Gene ID: 5358

UniProt: P13797