RAPGEF4 antibody (AA 1-210)

Catalog No. ABIN1682483

The Rabbit Polyclonal anti-RAPGEF4 antibody has been validated for WB. It is suitable to detect RAPGEF4 in samples from Human.

Quick Overview for RAPGEF4 antibody (AA 1-210) (ABIN1682483)

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPGEF4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAPGEF4 Antibody

Binding Specificity: AA 1-210

Sequence: MLYKKYRQYM AGLLAPPYGV METGSNNDRI PDKENTPLIE PHVPLRPANT ITKVPSEKIL RAGKILRNAI LSRAPHMIRD RKYHLKTYRQ CCVGTELVDW MMQQTPCVHS RTQAVGMWQV LLEDGVLNHV DQEHHFQDKY LFYRFLDDEH EDAPLPTEEE KKECDEELQD TMLLLSQMGP DAHMRMILRK PPGQRTVDDL EIIYEELLHI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human RAPGEF4 (NP_001093867.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RAPGEF4

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Alternative Name: RAPGEF4

Background: Guanine nucleotide exchange factor (GEF for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity.,RAPGEF4,CAMP-GEFII,CGEF2,EPAC,EPAC 2,EPAC2,Nbla00496,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,RAPGEF4

Molecular Weight: 79 kDa/96 kDa/98 kDa/99 kDa/115 kDa

Gene ID: 11069

UniProt: Q8WZA2

Pathways: Hormone Transport, Smooth Muscle Cell Migration