UFD1L
Reactivity: Human, Mouse, Rat
WB, IF (p), IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:100
Restrictions
For Research Use only
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
UFD1L
(Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
Alternative Name
UFD1L
Background
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.,UFD1,UFD1L,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,UFD1L