PA2G4 antibody (AA 201-320) (AbBy Fluor® 647)

Catalog No. ABIN1698988

This Rabbit Polyclonal antibody specifically detects PA2G4 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PA2G4 antibody (AA 201-320) (AbBy Fluor® 647) (ABIN1698988)

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PA2G4 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PA2G4 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 201-320

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep,Pig,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EBP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PA2G4

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Alternative Name: EBP1

Background:

Synonyms: AA672939, Cell cycle protein p38 2G4 homolog, Cell cycle protein p38-2G4 homolog, ErbB-3 binding protein 1, ErbB3 binding protein 1, ErbB3-binding protein 1, ErbB3-binding protein Ebp1, hG4 1, hG4-1, IRES-specic cellular trans-acting factor 45 kDa, MGC81621, MGC94070, Mpp1, p38 2G4, PA2G4, PA2G4_HUMAN, Plfap, proliferation associated 2G4, proliferation associated 2G4, 38-KD, proliferation-associated 2G4, 38 kDa, proliferation-associated 2G4, a, proliferation-associated protein 1, proliferation-associated protein 2G4, Protein p38-2G4, si:dz150i12.2, wu:fb19b11, wu:ft56d05, zgc:86732.

Background: EBP1 is a member of the peptidase M24C family and functions as an RNA-binding protein involved in cellular proliferation and differentiation processes. It is expressed in a variety of cell lines, including a wide range of tumor cell lines, and localizes to the cytoplasm. Upon treatment with Neuregulin-1 (heregulin), EBP1 translocates to the nucleus. EBP1 is a component of pre-ribosomal ribonucleoprotein complexes, participating in ribosome assembly and regulating the later steps of rRNA processing. In addition, EBP1 interacts with ErbB-3 and may function as a modulator of the ErbB-3-mediated signal transduction pathway by regulating the effects of Neuregulin-1 (heregulin). EBP1 also associates with histone deacetylases (HDACs), functioning as a transcriptional co-repressor of cell cycle regulatory genes.

Gene ID: 5036

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades