NPBWR1 antibody (AA 1-100) (Biotin)

Catalog No. ABIN1700328

This anti-NPBWR1 antibody is a Rabbit Polyclonal antibody detecting NPBWR1 in WB, ELISA, IHC (p), IHC (fro). Suitable for Mouse.

Quick Overview for NPBWR1 antibody (AA 1-100) (Biotin) (ABIN1700328)

Target: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPBWR1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NPBWR1 Antibody (Biotin)

Binding Specificity: AA 1-100

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NPBWR1

Target: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Alternative Name: GPR7

Background:

Synonyms: GPCR GPR7, G protein coupled receptor 7, g protein coupled receptor gpr7, GPR7, MGC129755, Neuropeptides B and W receptor 1, Neuropeptides B/W receptor 1, Neuropeptides B/W receptor type 1, NPB and NPW receptor 1, NPBWR1, opioid somatostatin like receptor 7.

Background: The two G protein-coupled receptors GPR7 and GPR8 display high similarity to each other. They both show high expression in brain and in particular in hypothalamus, and have been characterized as receptors for neuropeptide W (NPW) and neuropeptide B (NPB). In response to NPW and NPB, they play a role in the regulation of feeding behavior. GPR7 deficient mice develop an adult-onset obese phenotype that progressively worsens with age and is exacerbated when fed a high-fat diet. The genes encoding human GPR7 and GPR8 map to chromosomes 10q11.2-q21.1 and 10q13.3, respectively.

Gene ID: 2831