AKTIP antibody (AA 201-292) (Biotin)

Catalog No. ABIN1700666

The Rabbit Polyclonal anti-AKTIP antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect AKTIP in samples from Rat.

Quick Overview for AKTIP antibody (AA 201-292) (Biotin) (ABIN1700666)

Target: AKTIP (AKT Interacting Protein (AKTIP))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKTIP antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AKTIP Antibody (Biotin)

Binding Specificity: AA 201-292

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FTS/AKTIP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for AKTIP

Target: AKTIP (AKT Interacting Protein (AKTIP))

Alternative Name: FTS/AKTIP

Background:

Synonyms: AKT interacting protein, AKT-interacting protein, AKTIP, AKTIP_HUMAN, FT 1, FT1, Fused toes homolog, Fused toes protein homolog.

Background: Fused toes protein homolog (FTS), also known as AKT-interacting protein (AKTIP) and Ft1, is a 292 amino acid protein that localizes to the cytoplasm and the cell membrane. A member of the ubiquitin-conjugating enzyme family, FTS binds directly to AKT1 to regulate apoptosis in a cell population. AKT1 is a protein that plays a critical role in a number of cellular responses, such as cell growth, protein synthesis, and antiapoptotic signaling. The interaction of FTS and AKT1 enhances the phosphorylation and activation of AKT1, which, through an AKT1/GSK-3/NFATc1 signaling cascade, results in the increased production of the proapoptotic hormone Fas ligand and thus an increase in apoptosis.

Gene ID: 64400