LTB antibody (AA 171-244) (Biotin)

Catalog No. ABIN1701062

The Rabbit Polyclonal anti-LTB antibody has been validated for WB and ELISA. It is suitable to detect LTB in samples from Human.

Quick Overview for LTB antibody (AA 171-244) (Biotin) (ABIN1701062)

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTB antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-LTB Antibody (Biotin)

Binding Specificity: AA 171-244

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Lymphotoxin Beta

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for LTB

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Alternative Name: Lymphotoxin Beta

Background:

Synonyms: LT beta, LT-beta, LTB, lymphotoxin beta TNF superfamily, member 3, lymphotoxin beta, lymphotoxin-beta, OTTHUMP00000038214, p33, TNF C, TNF-C, TNFC, TNFC_HUMAN, TNFSF3, tumor necrosis factor C lymphotoxin beta, tumor necrosis factor C, tumor necrosis factor ligand superfamily member 3.

Background: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID: 4050

UniProt: Q06643

Pathways: NF-kappaB Signaling