GNRH1 antibody (AA 24-33) (Biotin)

Catalog No. ABIN1701318

The Biotin-conjugated Rabbit Polyclonal anti-GNRH1 antibody (ABIN1701318) specifically detects GNRH1 in ELISA, IHC (p) and IHC (fro). The antibody is reactive with Rat samples.

Quick Overview for GNRH1 antibody (AA 24-33) (Biotin) (ABIN1701318)

Target: GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNRH1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GNRH1 Antibody (Biotin)

Binding Specificity: AA 24-33

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Gonadoliberin-1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GNRH1

Target: GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))

Alternative Name: Gonadoliberin 1

Background:

Synonyms: GNRH, Gonadoliberin-1, Progonadoliberin-1, GON1_HUMAN, Progonadoliberin I, Gonadoliberin I, Gonadorelin, Gonadotropin-releasing hormone I, Luliberin I, Luteinizing hormone-releasing hormone I, LH-RH I, progonadoliberin-1 isoform 2 preproprotein, progonadoliberin-1 isoform 1 precursor, GNRH1, GRH, LHRH.

Background: The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012].

Gene ID: 2796

UniProt: P01148

Pathways: Hormone Activity