ECHDC2 antibody (AA 153-260) (Biotin)

Catalog No. ABIN1701497

The Rabbit Polyclonal anti-ECHDC2 antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect ECHDC2 in samples from Human.

Quick Overview for ECHDC2 antibody (AA 153-260) (Biotin) (ABIN1701497)

Target: ECHDC2 (Enoyl CoA Hydratase Domain Containing 2 (ECHDC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECHDC2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ECHDC2 Antibody (Biotin)

Binding Specificity: AA 153-260

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ECHDC2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ECHDC2

Target: ECHDC2 (Enoyl CoA Hydratase Domain Containing 2 (ECHDC2))

Alternative Name: ECHDC2

Background:

Synonyms: 1300017C12Rik, 2610009M20Rik, D4Ertd765e, Enoyl Coenzyme A hydratase domain containing 2, FLJ10948, Enoyl-CoA hydratase domain-containing protein 2, RGD1308525, RP23-379K6.3, ECHD2_HUMAN.

Background: ECHDC2 is a 292 amino acid mitochondrial protein that exists as two isoforms which are produced by alternative splicing events. The gene encoding ECHDC2 maps to chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 encodes a large number of disease-associated proteins, including Lamin A which, when expressed abnormally, can build up in the nucleus and cause nuclear blebs, a characteristic of the rare aging disease Hutchinson-Gilford progeria. Additionally, genes that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinsons Disease, Gaucher disease, schizophrenia and Usher syndrome are all located on chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Gene ID: 55268