FOXF2 antibody (AA 65-160) (Cy3)

Catalog No. ABIN1702285

This Rabbit Polyclonal antibody specifically detects FOXF2 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for FOXF2 antibody (AA 65-160) (Cy3) (ABIN1702285)

Target: FOXF2 (Forkhead Box F2 (FOXF2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXF2 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FOXF2 Antibody (Cy3)

Binding Specificity: AA 65-160

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXF2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FOXF2

Target: FOXF2 (Forkhead Box F2 (FOXF2))

Alternative Name: FOXF2

Background:

Synonyms: FKH L6, FKHL 6, FKHL6, Forkhead box F2, Forkhead box protein F2, Forkhead like 6, Forkhead related activator 2, Forkhead related protein FKHL6, Forkhead related transcription factor 2, FOX F2, FOXF 2, FREAC 2, FREAC2, OTTHUMP00000017863,

Background: The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF2 (forkhead box F2), also known as FKHL or FREAC2, is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. FOXF2 interacts with transcription factors TFIIB and TBP, and may be involved in regulating transcription in embryogenesis and pattern formation in multicellular organisms. FOXF2-deficient mice develop cleft palate and an abnormal tongue, which suggests that FOXF2 may be critical for palatogenesis.

Gene ID: 2295