CSNK1A1 antibody (pTyr294) (Cy3)

Catalog No. ABIN1702291

This Rabbit Polyclonal antibody specifically detects CSNK1A1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human and Rat.

Quick Overview for CSNK1A1 antibody (pTyr294) (Cy3) (ABIN1702291)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK1A1 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CSNK1A1 Antibody (Cy3)

Binding Specificity: pTyr294

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Casein Kinase 1 alpha around the phosphorylation site of Tyr294

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Background:

Synonyms: Casein Kinase 1 alpha phospho Y294, p-CK1A phospho Y294, Casein kinase 1 alpha 1, Casein kinase I isoform alpha, CK1, CK1A, CKI alpha, CKI-alpha, CKIa, Clock regulator kinase, Csnk1a1, Down regulated in lung cancer, HLCDGP1, KC1A_HUMAN, PRO2975.

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.

Gene ID: 1452

Pathways: WNT Signaling, Hedgehog Signaling