CTNND1 antibody (pTyr228) (Cy5)

Catalog No. ABIN1704077

The Rabbit Polyclonal anti-CTNND1 antibody has been validated for WB, IF (p) and IF (cc). It is suitable to detect CTNND1 in samples from Mouse.

Quick Overview for CTNND1 antibody (pTyr228) (Cy5) (ABIN1704077)

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNND1 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-CTNND1 Antibody (Cy5)

Binding Specificity: pTyr228

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Tyr228

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CTNND1

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Background:

Synonyms: delta 1 Catenin phospho Y228, p-delta 1 Catenin phospho Y228, Cadherin associated Src substrate, Cadherin-associated Src substrate, CAS, Catenin cadherin associated protein delta 1, Catenin delta 1, Catenin delta-1, CTND1_HUMAN, CTNND 1, CTNND, CTNND1, KIAA0384, p120, P120 CAS, p120 catenin, P120 CTN, p120Cas, p120Ctn, P120CAS, P120CTN.

Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Gene ID: 1500

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling