KIF13B antibody (AA 351-450) (Cy5)

Catalog No. ABIN1705164

This anti-KIF13B antibody is a Rabbit Polyclonal antibody detecting KIF13B in WB, IF (cc) and IF (p). Suitable for Mouse and Rat.

Quick Overview for KIF13B antibody (AA 351-450) (Cy5) (ABIN1705164)

Target: KIF13B (Kinesin Family Member 13B (KIF13B))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF13B antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-KIF13B Antibody (Cy5)

Binding Specificity: AA 351-450

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KIF13B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KIF13B

Target: KIF13B (Kinesin Family Member 13B (KIF13B))

Alternative Name: KIF13B

Background:

Synonyms: GAKIN, Guanylate kinase associated kinesin, KI13B_HUMAN, KIAA0639, K 13B, K13B, Kinesin 13B, Kinesin family member 13B, Kinesin like protein GAKIN, Kinesin like protein K13B, Kinesin-like protein GAKIN, Kinesin-like protein K13B, OTTHUMP00000225649.

Background: KIF13B is also known as Kinesin-like protein GAKIN or GAKIN and is a 1,826 amino acid protein that is widely expressed in tissues, with highest expression in brain and kidney. KIF13B is localized to the cytoplasm, as well as to the cytoskeleton, and is thought to be a microtubule-dependent motor protein which is able to bind to a variety of proteins in order to traffic them to various locations throughout the cell. KIF13B belongs to the kinesin-like protein family and possesses three domains typical of the kinesin-like protein family, namely an N-terminal motor domain with an ATP-binding motif, an FHA domain which is known to bind diverse cargos and a large stalk domain involved in protein-protein binding. Additionally, KIF13B has a microtubule-interacting sequence which is known as the CAP-Gly domain at its C-terminus. The CAP-Gly domain is highly conserved domain among eukaryotes, and in humans, defects in the CAP-Gly domain are implicated in many diseases affecting the trafficking of vesicles, neuromuscular junctions and lysosome proliferation.

Gene ID: 23303

UniProt: Q9NQT8