PIK3AP1 antibody (AA 601-700) (Cy5.5)

Catalog No. ABIN1705814

The Rabbit Polyclonal anti-PIK3AP1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect PIK3AP1 in samples from Human.

Quick Overview for PIK3AP1 antibody (AA 601-700) (Cy5.5) (ABIN1705814)

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3AP1 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PIK3AP1 Antibody (Cy5.5)

Binding Specificity: AA 601-700

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PIK3AP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PIK3AP1

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Alternative Name: Pik3ap1

Background:

Synonyms: B cell adaptor protein, B-cell adapter for phosphoinositide 3-kinase, B-cell phosphoinositide 3-kinase adapter protein 1, BCAP, BCAP_HUMAN, OTTHUMP00000020175, OTTHUMP00000020176, Phosphoinositide 3 kinase adaptor protein 1, Phosphoinositide 3-kinase adapter protein 1, PIK3AP1, RP11-34E5.3.

Background: B cell adaptor for phosphoinositide 3-kinase (BCAP) is a tyrosine kinase substrate that bridges B cell receptor (BCR) associated kinases to the PIK3 pathway. Syk, Btk or Lyn-dependent tyrosine phosphorylation of BCAP, provides binding sites for the p85 subunit of PIK3. BCAP mRNA is present in mouse spleen, thymus, liver, lung, macrophage and B cell lines. Human BCAP maps to chromosome 10q24.2.

Pathways: Activation of Innate immune Response, BCR Signaling, Warburg Effect