PRG2 antibody (AA 51-150) (Cy5.5)

Catalog No. ABIN1705819

This Rabbit Polyclonal antibody specifically detects PRG2 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for PRG2 antibody (AA 51-150) (Cy5.5) (ABIN1705819)

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRG2 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PRG2 Antibody (Cy5.5)

Binding Specificity: AA 51-150

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PRG2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PRG2

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Alternative Name: PRG2

Background:

Synonyms: BMPG, EMBP, Eosinophil granule major basic protein, Eosinophil major basic protein, MBP, MBP1, Natural killer cell activator, Pregnancy-associated major basic protein, PRG 2, PRG2, PRG2_HUMAN, Proteoglycan 2, Proteoglycan 2 bone marrow, Proteoglycan 2 preproprotein.

Background: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

Gene ID: 5553

UniProt: P13727