Stabilin 2 (STAB2) (AA 2201-2300) antibody (Cy5.5)

Catalog No. ABIN1706417

The Rabbit Polyclonal anti- antibody has been validated for IF (cc) and IF (p). It is suitable to detect in samples from Mouse.

Quick Overview for Stabilin 2 (STAB2) (AA 2201-2300) antibody (Cy5.5) (ABIN1706417)

Target: Stabilin 2 (STAB2)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Cy5.5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details

Binding Specificity: AA 2201-2300

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Stabilin-2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Stabilin 2 (STAB2)

Alternative Name: Stabilin 2/STAB 2

Background:

Synonyms: FEX2, HARE, FEEL2, FELL2, FELE-2, Stabilin-2, FAS1 EGF-like and X-link domain-containing adhesion molecule 2, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2, FEEL-2, Hyaluronan receptor for endocytosis, STAB2, FELL

Background: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.

Gene ID: 55576

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process