Dymeclin antibody (AA 151-250) (Cy5.5)

Catalog No. ABIN1706603

The Rabbit Polyclonal anti-Dymeclin antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect Dymeclin in samples from Human and Rat.

Quick Overview for Dymeclin antibody (AA 151-250) (Cy5.5) (ABIN1706603)

Target: Dymeclin (DYM)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dymeclin antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Dymeclin Antibody (Cy5.5)

Binding Specificity: AA 151-250

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Dymeclin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Dymeclin

Target: Dymeclin (DYM)

Alternative Name: Dymeclin

Background:

Synonyms: DMC, Dyggve-Melchior-Clausen syndrome protein, DYM, FLJ20071, FLJ90130, SMC, DYM_HUMAN.

Background: Dyggve-Melchior-Clausen syndrome (DMC), a rare autosomal recessive disorder, is characterized by microcephaly, short trunk dwarfism and sometime psychomotor retardation. Cutaneous cells of affected individuals show dilated rough endoplasmic reticulum and enlarged vacuoles. The Dyggve-Melchior-Clausen syndrome protein, also designated dymeclin, may play a role in proteoglycan metabolism and intracellular protein digestion. It is a widely expressed multi-pass membrane protein, detected primarily in chondrocytes and fetal brain tissue. Defects in dymeclin are also the cause of Smith-McCort dysplasis syndrome (SMC), which has characteristics identical to those of Dyggve-Melchior-Clausen syndrome.

Gene ID: 54808