CEP57L1 antibody (AA 131-230) (Cy5.5)

Catalog No. ABIN1706683

This Rabbit Polyclonal antibody specifically detects CEP57L1 in WB, IF (cc), IF (p). It exhibits reactivity toward Human.

Quick Overview for CEP57L1 antibody (AA 131-230) (Cy5.5) (ABIN1706683)

Target: CEP57L1 (Centrosomal Protein 57kDa-Like 1 (CEP57L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP57L1 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CEP57L1 Antibody (Cy5.5)

Binding Specificity: AA 131-230

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6ORF182

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CEP57L1

Target: CEP57L1 (Centrosomal Protein 57kDa-Like 1 (CEP57L1))

Alternative Name: C6orf182

Background:

Synonyms: BA487F23.2, Centrosomal protein of 57 kDa-related protein, Cep57-related protein, CEP57R, Chromosome 6 open reading frame 182, Hypothetical protein LOC285753, MGC21731, MGC70837, OTTHUMP00000016948,CE57L_HUMAN.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf182 gene product has been provisionally designated C6orf182 pending further characterization.

Gene ID: 285753

Pathways: Maintenance of Protein Location