MIXL1 antibody (AA 101-200) (Cy5.5)

Catalog No. ABIN1707124

This Rabbit Polyclonal antibody specifically detects MIXL1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for MIXL1 antibody (AA 101-200) (Cy5.5) (ABIN1707124)

Target: MIXL1 (Mix Paired-Like Homeobox (MIXL1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIXL1 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MIXL1 Antibody (Cy5.5)

Binding Specificity: AA 101-200

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MIXL1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MIXL1

Target: MIXL1 (Mix Paired-Like Homeobox (MIXL1))

Alternative Name: MIXL1

Background:

Synonyms: hMix, Homeobox protein MIXL1, Homeodomain protein 1, Homeodomain protein MIX, MILD1, MIX, Mix.1, Mix.1 homeobox-like protein, Mix1 homeobox-like 1, MIX1 homeobox-like protein 1, Mixl1, MIXL1_HUMAN.

Background: The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and in the control of gene expression. MIXL1 (Mix1 homeobox-like 1), also known as MIXL, is a 232 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in lymph tissues, MIXL1 functions as a transcription factor that plays an essential role in axial mesendoderm morphogenesis and endoderm formation and is also required for cellular differentiation during blood development. Additionally, MIXL1 is involved in maturation of heart and gut tissue during embryogenesis and may also act as a negative regulator of brachyury expression. Overexpression of MIXL1 is associated with non-Hodgkin and Hodgkin lymphomas, suggesting a role in carcinogenesis.

Gene ID: 83881