Filamin A antibody (pSer1084) (Cy5.5)

Catalog No. ABIN1707142

This Rabbit Polyclonal antibody specifically detects Filamin A in IF (p) and IF (cc). It exhibits reactivity toward Human.

Quick Overview for Filamin A antibody (pSer1084) (Cy5.5) (ABIN1707142)

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Filamin A antibody is conjugated to Cy5.5

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-Filamin A Antibody (Cy5.5)

Binding Specificity: pSer1084

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FLNA around the phosphorylation site of Ser1084

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Alternative Name: Filamin A

Background:

Synonyms: Filamin A phospho S1084, p-Filamin A phospho S1084, ABP 280, ABP 280 like protein, ABP-280, ABP280A, ABPA antibody Actin binding like protein, Actin binding protein 280, Actin-binding protein 280, Alpha filamin, Alpha-filamin, APBX, cb967, Dilp2, Endothelial actin binding protein, Endothelial actin-binding protein, Filamin 1, Filamin A alpha actin binding protein 280, Filamin A, Filamin-1, Filamin-A, FLN, FLN-A, FLN1, FLNA, FLNA_HUMAN, FMD, MNS, NHBP, Non muscle filamin, Non-muscle filamin, OPD, OPD1, OPD2.

Background: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking.

Gene ID: 2316

Pathways: TCR Signaling, Maintenance of Protein Location