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EIF2C3 antibody (AA 251-350) (Cy7)

The Rabbit Polyclonal anti-EIF2C3 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect EIF2C3 in samples from Cow and Zebrafish (Danio rerio).
Catalog No. ABIN1708550

Quick Overview for EIF2C3 antibody (AA 251-350) (Cy7) (ABIN1708550)

Target

See all EIF2C3 Antibodies
EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Reactivity

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  • 15
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
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Cow, Zebrafish (Danio rerio)

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This EIF2C3 antibody is conjugated to Cy7

Application

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

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    AA 251-350

    Cross-Reactivity

    Cow, Zebrafish (Danio rerio)

    Predicted Reactivity

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Argonaute 3/eIF2C3

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

    Alternative Name

    Argonaute 3/e2C3

    Background

    Synonyms: Argonaute 3/e2C 3, 5730550L01Rik, Ago 3, Ago3, AGO3_HUMAN, argonaute 3, Argonaute3, e 2C 3, e-2C 3, e2C 3, E2c3, e2C3, E2C3 protein, Eukaryotic translation initiation factor 2C 3, Eukaryotic translation initiation factor 2C3, FLJ12765, hAgo3, MGC86946, Protein argonaute-3.

    Background: Eukaryotic translation initiation factor 2C (eIF2C) proteins (argonaute family) influence RNA interference (RNAi) as components of the RNA-inducible silencing complex (RISC) or microRNA (miRNA)-containing ribonucleoprotein particle (miRNP). Small RNAs, including small interfering RNAs (siRNAs) and miRNAs, can silence target genes through mechanisms that utilize RISC or miRNP particles. eIF2C1 (argonaute 1, AGO1, eIF2C, GERP95, Q99) and Dicer1 play a coordinated role in siRNA-mediated gene silencing. eIF2C2 (Slicer, argonaute 2, AGO2, Q10) is a RISC component that can concentrate in cytoplasmic processing bodies (P-bodies) and catalyze mRNA cleavage. Mammalian P-bodies contain mRNAs and have an association with miRNA-induced translational silencing and siRNA-induced mRNA degradation. Additional eIF2C proteins include eIF2C3 (argonaute 3, AGO3), eIF2C4 (argonaute 4, AGO4) and meIF2c5 (mouse argonaute 5).

    Gene ID

    192669

    Pathways

    Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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