Sorting Nexin 7 antibody (AA 151-250) (Cy7)

Catalog No. ABIN1708764

This anti-Sorting Nexin 7 antibody is a Rabbit Polyclonal antibody detecting Sorting Nexin 7 in IF (cc) and IF (p). Suitable for Human.

Quick Overview for Sorting Nexin 7 antibody (AA 151-250) (Cy7) (ABIN1708764)

Target: Sorting Nexin 7 (SNX7)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorting Nexin 7 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Sorting Nexin 7 Antibody (Cy7)

Binding Specificity: AA 151-250

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNX7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Sorting Nexin 7

Target: Sorting Nexin 7 (SNX7)

Alternative Name: SNX7

Background:

Synonyms: MGC8717, DKFZP564F052, MGC8717, MGC8717, , Sorting nexin 7, Sorting nexin 7 isoform a, SNX7_HUMAN.

Background: Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNXs partially associate with cellular membranes, despite their hydrophilic nature. SNX7 is unique in that it does not have a coiled coil region like some of the SNX family members. Mutations in the SNX7 gene have not been shown to cause any diseases.

Gene ID: 51375