CSRP2 antibody (AA 101-193) (HRP)

Catalog No. ABIN1711601

The Rabbit Polyclonal anti-CSRP2 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect CSRP2 in samples from Human.

Quick Overview for CSRP2 antibody (AA 101-193) (HRP) (ABIN1711601)

Target: CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSRP2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CSRP2 Antibody (HRP)

Binding Specificity: AA 101-193

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CSRP2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CSRP2

Target: CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))

Alternative Name: CSRP2

Background:

Synonyms: CRP 2, CRP2, CSRP2, CSRP2_HUMAN, Cysteine and glycine rich protein 2, Cysteine and glycine-rich protein 2, Cysteine rich protein 2, Cysteine-rich protein 2, LIM domain only 5 smooth muscle, LIM domain only protein 5, LMO 5, LMO-5, LMO5, SmLIM, Smooth muscle cell LIM protein.

Background: CRP2 is a 193 amino acid nuclear protein that belongs to the CRP family of LIM domain proteins. Highly expressed in smooth muscle of aorta, CRP2 is thought to have a role in embryonic vascular system development and is downregulated following cell injury or PDGF-B exposure. CRP2 contains two LIM zinc-binding domains and is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Gene ID: 1466