C8ORF74 antibody (AA 31-130) (HRP)

Catalog No. ABIN1712218

This Rabbit Polyclonal antibody specifically detects C8ORF74 in ELISA, WB, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for C8ORF74 antibody (AA 31-130) (HRP) (ABIN1712218)

Target: C8ORF74 (Chromosome 8 Open Reading Frame 74 (C8ORF74))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8ORF74 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C8ORF74 Antibody (HRP)

Binding Specificity: AA 31-130

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C8orf74

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C8ORF74

Target: C8ORF74 (Chromosome 8 Open Reading Frame 74 (C8ORF74))

Alternative Name: C8orf74

Background:

Synonyms: C8orf74, CH074_HUMAN, Uncharacterized protein C8orf74.

Background: C8orf74 (chromosome 8 open reading frame 74) is a 294 amino acid protein encoded by a gene that maps to human chromosome 8p23.1. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Gene ID: 203076