GALM antibody (AA 251-342) (HRP)

Catalog No. ABIN1712529

This anti-GALM antibody is a Rabbit Polyclonal antibody detecting GALM in WB, ELISA, IHC (p) and IHC (fro). Suitable for Rat.

Quick Overview for GALM antibody (AA 251-342) (HRP) (ABIN1712529)

Target: GALM (Galactose Mutarotase (Aldose 1-Epimerase) (GALM))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALM antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GALM Antibody (HRP)

Binding Specificity: AA 251-342

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GALM/Galactose mutarotase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GALM

Target: GALM (Galactose Mutarotase (Aldose 1-Epimerase) (GALM))

Alternative Name: GALM/Galactose mutarotase

Background:

Synonyms: Aldose 1 epimerase, Aldose 1-epimerase, BLOCK25, Galactomutarotase, Galactose mutarotase, Galm, GALM_HUMAN, IBD1.

Background: Galactose Mutarotase is a member of the aldose epimerase family and is involved in hexose metabolism. Through its catalytic activity, Galactose Mutarotase converts beta-aldose to alpha-aldose on several sugars, including D-glucose, L-arabinose and D-xylose. Found in the cytoplasm of most cells, Galactose Mutarotase plays a key role in galactose metabolism by catalyzing the conversion of beta-D-galactose to alpha-D-galactose. The enzyme contains two residues, Glu 304 and His 170, that are critical for catalysis, as well as His 96 and Asp 243, which are important for proper substrate recognition by the active site. No known diseases have been associated with mutations in the Galactose Mutarotase gene, although inhibition of Galactose Mutarotase activity could potentially be associated with a build-up of unmetabolized sugars during metabolism.

Gene ID: 130589