Ectodysplasin A antibody (AA 101-200) (PE)

Catalog No. ABIN1712702

The Rabbit Polyclonal anti-Ectodysplasin A antibody has been validated for WB and FACS. It is suitable to detect Ectodysplasin A in samples from Human and Mouse. There is 1 publication available.

Quick Overview for Ectodysplasin A antibody (AA 101-200) (PE) (ABIN1712702)

Target: Ectodysplasin A (EDA)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Ectodysplasin A Antibody (PE)

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ectodysplasin-A, membrane form/secreted form

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-Ectodysplasin A antibody (PE) (ABIN1712702)

Sisto, Barca, Lofrumento, Lisi: "Downstream activation of NF-κB in the EDA-A1/EDAR signalling in Sjögren's syndrome and its regulation by the ubiquitin-editing enzyme A20." in: Clinical and experimental immunology, Vol. 184, Issue 2, pp. 183-96, (2016) (PubMed).

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: EDA/Ectodermal dysplasia protein

Background:

Synonyms: ED1, HED, EDA1, EDA2, HED1, ODT1, XHED, ECTD1, XLHED, ED1-A1, ED1-A2, EDA-A1, EDA-A2, TNLG7C, STHAGX1, Ectodysplasin-A, Ectodermal dysplasia protein, EDA protein, EDA

Background: Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.

Gene ID: 1896

UniProt: Q92838

Pathways: Tube Formation