ACTR1 antibody (PE)

Catalog No. ABIN1712775

This anti-ACTR1 antibody is a Rabbit Polyclonal antibody detecting ACTR1 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for ACTR1 antibody (PE) (ABIN1712775)

Target: ACTR1 (ARP1 Actin-Related Protein 1, Centractin (ACTR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTR1 antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-ACTR1 Antibody (PE)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SKR1/ACTR1

Isotype: IgG

Application Details

Application Notes: FCM: 1:20-100
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ACTR1

Target: ACTR1 (ARP1 Actin-Related Protein 1, Centractin (ACTR1))

Alternative Name: Actr1

Background:

Synonyms: Activin Receptor Type IA, Activin A receptor type I, Activin A receptor type II like kinase 2, Activin receptor type I, Activin receptor type-1, Activin receptor-like kinase 2, ACTR1, ACTR 1, ACTR-1, ACTR-I, ACTRI, ACVR 1, ACVR1, ACVR1_HUMAN, ACVR1A, ACVRLK 2, ACVRLK2, ALK 2, ALK-2, ALK2, FOP, Hydroxyalkyl protein kinase, Serine/threonine protein kinase receptor R1, Serine/threonine-protein kinase receptor R1, SKR 1, SKR1, TGF-B superfamily receptor type I, TGFB superfamily receptor type I, TSR-I, TSRI, TSRI.

Background: Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (16). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

Gene ID: 90