QRFPR antibody (PE-Cy5)

Catalog No. ABIN1712963

The Rabbit Polyclonal anti-QRFPR antibody has been validated for WB. It is suitable to detect QRFPR in samples from Human, Mouse and Rat.

Quick Overview for QRFPR antibody (PE-Cy5) (ABIN1712963)

Target: QRFPR (Pyroglutamylated RFamide Peptide Receptor (QRFPR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QRFPR antibody is conjugated to PE-Cy5

Application: Western Blotting (WB)

Product Details anti-QRFPR Antibody (PE-Cy5)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 103

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for QRFPR

Target: QRFPR (Pyroglutamylated RFamide Peptide Receptor (QRFPR))

Alternative Name: GPR103

Background:

Synonyms: AQ27, G protein coupled receptor 103, G-protein coupled receptor 103, G protein-coupled receptor 103, Orexigenic neuropeptide QRFP receptor, Pyroglutamylated RFamide peptide receptor, QRFP receptor, QRFPR, SP9155, QRFPR_HUMAN, GPCR GPR103.

Background: G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR103 is a 455-amino acid protein with highest expression in the brain, retina, trigeminal ganglion, hypothalamus and vestibular nucleus. In peripheral tissues, GPR103 is expressed only in the heart, kidney and testis. GPR103 may regulate adrenal function. A hypothalamic neuropeptide of the RFamide family (26RFa) acts as an endogenous ligand for GPR103.

Gene ID: 84109