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Ggt5 Heavy Chain antibody (PE-Cy5)

The Rabbit Polyclonal anti- antibody has been validated for WB. It is suitable to detect in samples from Human, Mouse, Rat and Cow.
Catalog No. ABIN1712996

Quick Overview for Ggt5 Heavy Chain antibody (PE-Cy5) (ABIN1712996)

Target

Ggt5 Heavy Chain

Reactivity

Human, Mouse, Rat, Cow

Host

  • 18
Rabbit

Clonality

  • 18
Polyclonal

Conjugate

  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
PE-Cy5

Application

  • 18
  • 13
  • 13
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB)
  • Predicted Reactivity

    Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 5 heavy chain

    Isotype

    IgG
  • Application Notes

    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Ggt5 Heavy Chain

    Background

    Synonyms: Gamma glutamyl transpeptidase related enzyme, Gamma glutamyltranspeptidase 5, Gamma-glutamyl transpeptidase-related enzyme, Gamma-glutamyltransferase 5 heavy chain, Gamma-glutamyltransferase-like activity 1, Gamma-glutamyltranspeptidase 5, GGT 5, GGT REL, GGT-rel, GGT5, GGT5_HUMAN, DKFZP566O011, GGTLA1, Glutathione hydrolase 5, Leukotriene-C4 hydrolase, Gamma-glutamyltransferase 5 heavy chain.

    Background: g-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors. This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion. In humans, hepatic GGT activity is elevated in some liver diseases. GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma. GGT5 converts Leukotriene C4 to Leukotriene D4, it does not, however, convert synthetic substrates that are commonly used to assay GGT. In human serum and tissues there is a marked heterogeneity in GGT, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes.

    Gene ID

    2687

    UniProt

    P36269
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