CDHR4 antibody (AA 501-600)

Catalog No. ABIN1713463

This Rabbit Polyclonal antibody specifically detects CDHR4 in ELISA, ICC, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CDHR4 antibody (AA 501-600) (ABIN1713463)

Target: CDHR4 (Cadherin-Related Family Member 4 (CDHR4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDHR4 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CDHR4 Antibody

Binding Specificity: AA 501-600

Predicted Reactivity: Human,Mouse,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDH29

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CDHR4

Target: CDHR4 (Cadherin-Related Family Member 4 (CDHR4))

Alternative Name: CDH29

Background:

Synonyms: Cadherin-like protein 29, Cadherin-related family member 4, CDH29, CDHR4, CDHR4_HUMAN, UNQ9392/PRO34300, VLLR9392.

Background: The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-29, also known as Cadherin-related family member 4, is a 788 amino acid single-pass type I membrane protein that has four cadherin domains. There are two isoforms of cadherin-29 that are produced as a result of alternative splicing events. The gene encoding cadherin-29 maps to human chromosome 3, which is is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells.