DTYMK antibody (AA 1-100)

Catalog No. ABIN1714357

This Rabbit Polyclonal antibody specifically detects DTYMK in WB, ELISA, ICC, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for DTYMK antibody (AA 1-100) (ABIN1714357)

Target: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTYMK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DTYMK Antibody

Binding Specificity: AA 1-100

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DTYMK/CDC8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DTYMK

Target: DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))

Alternative Name: DTYMK/CDC8

Background:

Synonyms: CDC8, Deoxythymidylate kinase thymidylate kinase, deoxythymidylate kinase, dTMP kinase, Dtymk, FLJ44192, KTHY_HUMAN, MGC198617, OTTHUMP00000164604, OTTHUMP00000200145, OTTHUMP00000200146, PP3731, Thymidylate kinase, TMPK, TYMK.

Background: DTYMK is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.

Gene ID: 1841

Pathways: Nucleotide Phosphorylation