FOXN2 antibody (AA 51-150)

Catalog No. ABIN1714615

This Rabbit Polyclonal antibody specifically detects FOXN2 in WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Mouse.

Quick Overview for FOXN2 antibody (AA 51-150) (ABIN1714615)

Target: FOXN2 (Forkhead Box N2 (FOXN2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-FOXN2 Antibody

Binding Specificity: AA 51-150

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXN2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FOXN2

Target: FOXN2 (Forkhead Box N2 (FOXN2))

Alternative Name: FOXN2

Background:

Synonyms: 3230402J05Rik, 6030465J18Rik, Fkh19, Forkhead box N2, Forkhead box protein N2, Foxn1, foxn2, FOXN2_HUMAN, HTLF, Human T-cell leukemia virus enhancer factor.

Background: The forkhead domain-containing gene family (Fox) comprises over 20 members in mammals and is defined by a conserved 110 amino-acid motif containing a winged helix structure DNA-binding domain. The members of this gene family have been implicated as key regulators of embryogenesis, cell cycling, cell lineage restriction and cancer. As such, FOXN2 contains a domain with homology to the forkhead DNA binding domain. FOXN2, or Human T-cell leukemia virus enhancer factor, is a 341 amino acid protein mapping to human gene FOXN2, which has been localized to human chromosome 2p16-p22. This protein, encoded by a 1239-bp cDNA isolated from the Jurkat cDNA library, is capable of binding to a region of the human T-cell leukemia virus long terminal repeat (HTLV-I LTR) located between amino acids 155 and 117. This purine-rich region is important in the regulation of gene expression by the Ets family of transcription factors. FOXN2 is a unique cellular gene that may function in the transcriptional regulation of HTLV-I LTR.

Gene ID: 3344