SNX9 antibody (AA 501-595)

Catalog No. ABIN1714873

This Rabbit Polyclonal antibody specifically detects SNX9 in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for SNX9 antibody (AA 501-595) (ABIN1714873)

Target: SNX9 (Sorting Nexin 9 (SNX9))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SNX9 Antibody

Binding Specificity: AA 501-595

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNX9

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SNX9

Target: SNX9 (Sorting Nexin 9 (SNX9))

Alternative Name: SNX9/SH3PX1

Background:

Synonyms: SDP1, WISP, SH3PX1, SH3PXD3A, Sorting nexin-9, SH3 and PX domain-containing protein 1, Protein SDP1, SH3 and PX domain-containing protein 3A, SNX9

Background: Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.

Gene ID: 51429

UniProt: Q9Y5X1