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Chromogranin A antibody (AA 87-252)

CHGA Reactivity: Human FACS, WB, ELISA, ICC Host: Mouse Monoclonal 1A6B6 unconjugated
Catalog No. ABIN1724755
  • Target See all Chromogranin A (CHGA) Antibodies
    Chromogranin A (CHGA)
    Binding Specificity
    • 19
    • 15
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 87-252
    Reactivity
    • 208
    • 75
    • 69
    • 30
    • 29
    • 15
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 116
    • 98
    • 5
    • 1
    Mouse
    Clonality
    • 127
    • 92
    Monoclonal
    Conjugate
    • 101
    • 16
    • 11
    • 10
    • 10
    • 10
    • 10
    • 10
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Chromogranin A antibody is un-conjugated
    Application
    • 111
    • 106
    • 75
    • 69
    • 60
    • 49
    • 36
    • 14
    • 13
    • 12
    • 11
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Purpose
    CHGA Antibody
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human CHGA (AA: 87-252 ) expressed in E. Coli.
    Clone
    1A6B6
    Isotype
    IgG1
    Top Product
    Discover our top product CHGA Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/50

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Mergler, Skrzypski, Sassek, Pietrzak, Pucci, Wiedenmann, Strowski: "Thermo-sensitive transient receptor potential vanilloid channel-1 regulates intracellular calcium and triggers chromogranin A secretion in pancreatic neuroendocrine BON-1 tumor cells." in: Cellular signalling, Vol. 24, Issue 1, pp. 233-46, (2011) (PubMed).

    El Ali, Fichna, Piniewska, Kosowicz, Grzymis?awski: "Chromogranin A as a useful neuroendocrine marker in patients with autoimmune Addison's disease." in: Journal of endocrinological investigation, Vol. 33, Issue 3, pp. 186-91, (2010) (PubMed).

  • Target
    Chromogranin A (CHGA)
    Alternative Name
    CHGA (CHGA Products)
    Background
    The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

    Molecular Weight
    50.7 kDa
    Gene ID
    1113
    UniProt
    P10645
    Pathways
    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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