MRPL42 antibody (AA 10-142)

Catalog No. ABIN1724819

The Mouse Monoclonal anti-MRPL42 antibody has been validated for ELISA, IHC, WB and FACS. It is suitable to detect MRPL42 in samples from Human. There are 2+ publications available.

Quick Overview for MRPL42 antibody (AA 10-142) (ABIN1724819)

Target: MRPL42 (Mitochondrial Ribosomal Protein L42 (MRPL42))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MRPL42 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)

Clone: 3H6H2

Product Details anti-MRPL42 Antibody

Binding Specificity: AA 10-142

Purpose: MRPL42 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MRPL42 (AA: 10-142) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MRPL42 antibody (ABIN1724819)

Zhang, Gerstein: "Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome." in: Genomics, Vol. 81, Issue 5, pp. 468-80, (2003) (PubMed).

Koc, Burkhart, Blackburn, Moyer, Schlatzer, Moseley, Spremulli: "The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present." in: The Journal of biological chemistry, Vol. 276, Issue 47, pp. 43958-69, (2001) (PubMed).

Target Details for MRPL42

Target: MRPL42 (Mitochondrial Ribosomal Protein L42 (MRPL42))

Alternative Name: MRPL42

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.

Molecular Weight: 16.6 kDa

Gene ID: 28977

UniProt: Q9Y6G3