ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) antibody

Details for Product No. ABIN1731527
Antigen
Reactivity
Human
138
64
50
10
9
7
6
5
4
3
3
3
3
1
Host
Rabbit
126
21
4
Clonality
Polyclonal
Conjugate
Un-conjugated
10
7
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
90
38
33
29
15
13
5
4
3
2
1
1
Options
Immunogen Synthetic 15 amino acid peptide from Disintegrin-like domain of human ADAMTS4. Percent identity with other species by BLAST analysis: Human (100%), Orangutan (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Mouse (100%), Hamster (100%)
Isotype IgG
Specificity Reacts with human ADAMTS4
Cross-Reactivity (Details) BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purification Antigen affinity purified
Antigen
Alternative Name ADAMTS4 (ADAMTS4 Antibody Abstract)
Background Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
UniProt O75173
Application Notes

Working dilution: IHC - P (2 μg/mL

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, Sodium azide 0.1 %
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-80 °C
Storage Comment Long term: -70°C, Short term: +4°C
Supplier Images
Image no. 1 for anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) antibody (ABIN1731527) anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) antibody