ADRB3 antibody (Extracellular Domain, N-Term)

Catalog No. ABIN1731586

This Rabbit Polyclonal antibody specifically detects ADRB3 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for ADRB3 antibody (Extracellular Domain, N-Term) (ABIN1731586)

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRB3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADRB3 Antibody

Binding Specificity: Extracellular Domain, N-Term

Specificity: Reacts with human ADRB3

Cross-Reactivity (Details): BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Antigen affinity purified

Immunogen: Synthetic 20 amino acid peptide from N-terminal extracellular domain of human ADRB3. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (95%), Guinea pig (90%), Monkey (85%), Elephant (85%), Rabbit (85%)

Isotype: IgG

Application Details

Application Notes:

Working dilution: IHC - P (17 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Long term: -70°C, Short term: +4°C

Target Details for ADRB3

Target: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Alternative Name: ADRB3

Background: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.

UniProt: P13945

Pathways: cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation