NOG antibody (AA 156-170)

Catalog No. ABIN1737419

The Rabbit Polyclonal anti-NOG antibody has been validated for WB. It is suitable to detect NOG in samples from Human, Mouse and Rat.

Quick Overview for NOG antibody (AA 156-170) (ABIN1737419)

Target: NOG (Noggin (NOG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NOG Antibody

Binding Specificity: AA 156-170

Specificity: Reacts with Noggin from human, mouse and rat

Purification: Antigen affinity purified

Immunogen: Synthetic peptide comprising residues 156-170 [PVLYAWNDLGSRFWP] of the human Noggin protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/1 000 to 1/2 000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for NOG

Target: NOG (Noggin (NOG))

Alternative Name: Noggin

Background: Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin, and 2) Noggin, which is a bone morphogenetic protein inhibitor.Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Pathways: Stem Cell Maintenance, Tube Formation