PARP2 antibody (Poly (ADP-Ribose) Polymerase 2) AA 43-59 Primary Antibody
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- Target See all PARP2 Antibodies
- PARP2
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Binding Specificity
- AA 43-59
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PARP2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- Reacts with human PARP 2
- Purification
- Purified
- Immunogen
- Residues 43-59 [QRQESKKMPVAGGKANK] of the 62 kDa human PARP-2 protein.
- Isotype
- IgG
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- Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- WB : 1/500 to 1/1000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, Sodium azide 0.02 %
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 6 months
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- Target
- PARP2
- Alternative Name
- PARP2 (PARP2 Products)
- Synonyms
- ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2, Adprt2, Adprtl2, Aspartl2, C78626, cb996, adprtl2, ADPRT-2, APP, ATPARP1, PARP1, POLY(ADP-RIBOSE) POLYMERASE, POLY(ADP-RIBOSE) POLYMERASE 1, PP, T14P8.19, T14P8_19, poly(ADP-ribose) polymerase, poly(ADP-ribose) polymerase 2, poly(ADP-ribose) polymerase 2, poly (ADP-ribose) polymerase family, member 2, poly (ADP-ribose) polymerase 2, poly(ADP-ribose) polymerase 2 S homeolog, poly(ADP-ribose) polymerase, PARP2, Parp2, parp2, parp2.S
- Background
- Poly(ADP-ribose) polymerase 1, (PARP-1) and poly(ADP-ribose) polymerase 2 (PARP-2) catalyze the formation of poly(ADP-ribose) polymers in a DNA-dependent manner. PARP-2 displays automodification properties similar to PARP-1. These act by poly(ADP-ribosylation), which is a post-translational modification of nuclear proteins in response to DNA damage that activates the base excision repair machinery.
- Pathways
- DNA Damage Repair