PARP2 antibody (AA 450-550)

Catalog No. ABIN7269442

This Rabbit Polyclonal antibody specifically detects PARP2 in WB. It exhibits reactivity toward Human.

Quick Overview for PARP2 antibody (AA 450-550) (ABIN7269442)

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PARP2 Antibody

Binding Specificity: AA 450-550

Purpose: PARP2 Rabbit pAb

Sequence: FADMSSKSAN YCFASRLKNT GLLLLSEVAL GQCNELLEAN PKAEGLLQGK HSTKGLGKMA PSSAHFVTLN GSTVPLGPAS DTGILNPDGY TLNYNEYIVY N

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 450-550 of human PARP2 (NP_001036083.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Alternative Name: PARP2

Background: This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.,PARP2,ADPRT2,ADPRTL2,ADPRTL3,ARTD2,PARP-2,pADPRT-2,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,PARP2

Molecular Weight: 64kDa/66kDa

Gene ID: 10038

UniProt: Q9UGN5

Pathways: DNA Damage Repair