S1PR1 antibody (1st Cytoplasmic Domain)

Catalog No. ABIN1739013

This anti-S1PR1 antibody is a Rabbit Polyclonal antibody detecting S1PR1 in IHC (p). Suitable for Human.

Quick Overview for S1PR1 antibody (1st Cytoplasmic Domain) (ABIN1739013)

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S1PR1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-S1PR1 Antibody

Binding Specificity: 1st Cytoplasmic Domain

Specificity: Reacts with the cytoplasmic domain of human S1PR1 / EDG1

Cross-Reactivity (Details): BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Antigen affinity purified

Immunogen: Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human S1PR1 / EDG1. Percent identity with other species by BLAST analysis: Human, Platypus (100%), Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Panda, Horse, Opossum, Turkey, Lizard, Xenopus (94%), Shrew, Cat, Elephant, Pig (88%), Zebrafish (81%).

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
IHC-P (3 μg/mL - 6

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Long term: -70°C, Short term: +4°C

Target Details for S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Alternative Name: S1PR1 / EDG1

Background: Play a role in angiogenesis and in chemotaxis. S1PR1 is a protein involved in the regulation of endothelial cell development.

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2