SNAPIN antibody (C-Term)

Catalog No. ABIN1742322

This anti-SNAPIN antibody is a Rabbit Polyclonal antibody detecting SNAPIN in WB. Suitable for Human, Mouse and Rat. This Primary Antibody has been cited in 4+ publications.

Quick Overview for SNAPIN antibody (C-Term) (ABIN1742322)

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAPIN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNAPIN Antibody

Binding Specificity: AA 117-136, C-Term

Specificity: Specific for snapin.

Immunogen: Synthetic peptide TARRRAMLDSGVYPPGSPSK (aa 117-136 in rat) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Application Details

Application Notes: WB: 1:100 up to 1:5000, IP: not recommended IHC: not recommended

Comment:

Since snapin is present in very low concentrations long exposure time is recommended.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 200µl H2O.

Preservative: Azide and BSA free

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: 4 °C/-20 °C

Storage Comment: Reconstitute and aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized.

References for anti-SNAPIN antibody (ABIN1742322)

Zhou, Cai, Xie, Sheng: "Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons." in: Cell reports, Vol. 2, Issue 1, pp. 42-51, (2012) (PubMed).

Zhang, Wada, Yasuhara, Iseda, Eguchi, Fukui, Yang, Yamagata, Hiesberger, Igarashi, Zhang, Wang, Akagi, Kanwar, Makino: "The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells." in: PLoS ONE, Vol. 2, Issue 5, pp. e414, (2007) (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Vites, Rhee, Schwarz, Rosenmund, Jahn: "Reinvestigation of the role of snapin in neurotransmitter release." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26251-6, (2004) (PubMed).

Target Details for SNAPIN

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Alternative Name: Snapin

Background: Synonyms: Snapap

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis