PVALB antibody

Catalog No. ABIN1742405

The Rabbit Polyclonal anti-PVALB antibody has been validated for WB, IHC, IP and IHC (p). It is suitable to detect PVALB in samples from Human, Rat, Mouse and Grasshopper. There are 3+ publications available.

Quick Overview for PVALB antibody (ABIN1742405)

Target: PVALB (Parvalbumin (PVALB))

Reactivity: Human, Rat, Mouse, Grasshopper

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PVALB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PVALB Antibody

Purpose: Rabbit anti-Parvalbumin antiserum

Specificity: Specific for parvalbumin.

Cross-Reactivity (Details): Reacts with: human (P20472), rat (P02625), mouse (P32848), grashopper. Other species not tested yet.

Purification: antiserum

Immunogen: Full-length recombinant rat Parvalbumin (UniProt Id: P02625)

Application Details

Application Notes: WB:1 : 5000 up to 1 : 10000 , IP:yes ICC:not tested yet IHC:1 : 500 up to 1 : 1000, IHC-P:1 : 500,

Comment:

WB: Due to its small size a tricine gel is recommended.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-PVALB antibody (ABIN1742405)

Hadar, Edemann-Callesen, Reinel, Wieske, Voget, Popova, Sohr, Avchalumov, Priller, van Riesen, Puls, Bader, Winter: "Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders." in: Scientific reports, Vol. 6, pp. 39145, (2018) (PubMed).

Nieto-Gonzalez, Jensen: "BDNF Depresses Excitability of Parvalbumin-Positive Interneurons through an M-Like Current in Rat Dentate Gyrus." in: PLoS ONE, Vol. 8, Issue 6, pp. e67318, (2016) (PubMed).

Li, Su, Wang, Zhao, Liao, Wang, Si: "Repeated Blockade of NMDA Receptors During Adolescence Impairs Reversal Learning and Disrupts GABAergic Interneurons in Rat Medial Prefrontal Cortex." in: Frontiers in molecular neuroscience, Vol. 9, pp. 17, (2016) (PubMed).

Target Details for PVALB

Target: PVALB (Parvalbumin (PVALB))

Alternative Name: Parvalbumin

Background:

Synonyms: Pvalb, Parv

Antigen Information: Parvalbumin is calcium binding protein specific for a subpopulation of GABAergic interneurones

UniProt: P02625