Tenascin R antibody

Catalog No. ABIN1742431

This Mouse Monoclonal antibody specifically detects Tenascin R in IHC, WB and ICC. It exhibits reactivity toward Rat, Mouse, Chicken and Cow and has been mentioned in 4+ publications.

Quick Overview for Tenascin R antibody (ABIN1742431)

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Reactivity: Rat, Mouse, Chicken, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tenascin R antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC)

Grade: KO Validated

Clone: 619

Product Details anti-Tenascin R Antibody

Purpose: Mouse anti-Tenascin-R IgG

Specificity: Specific for Tenascin-R.

Cross-Reactivity (Details): Reacts with: rat (Q05546), mouse (Q8BYI9), cow, chicken. Other species not tested yet.

Purification: purified IgG

Immunogen: full length bovine Tenascin-R isolated from brain (UniProt Id: E1BKN2)

Isotype: IgG1

Application Details

Application Notes: WB:1 : 1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References for anti-Tenascin R antibody (ABIN1742431)

Arranz, Perkins, Irie, Lewis, Hrabe, Xiao, Itano, Kimata, Hrabetova, Yamaguchi: "Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 18, pp. 6164-76, (2014) (PubMed).

Apostolova, Irintchev, Schachner: "Tenascin-R restricts posttraumatic remodeling of motoneuron innervation and functional recovery after spinal cord injury in adult mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 30, pp. 7849-59, (2006) (PubMed).

Schuster, Krug, Stalder, Hackel, Gerardy-Schahn, Schachner et al.: "Immunoelectron microscopic localization of the neural recognition molecules L1, NCAM, and its isoform NCAM180, the NCAM-associated polysialic acid, beta1 integrin and the extracellular matrix ..." in: Journal of neurobiology, Vol. 49, Issue 2, pp. 142-58, (2001) (PubMed).

Weber, Bartsch, Rasband, Czaniera, Lang, Bluethmann, Margolis, Levinson, Shrager, Montag, Schachner: "Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 11, pp. 4245-62, (1999) (PubMed).

Target Details for Tenascin R

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Alternative Name: Tenascin-R

Background:

Synonyms: TNR, J1-160/180, Janusin, Restrictin, Cell Adhesion Proteins

Antigen Information: K.O. Tenascin-R is a multidomain adhesion molecule

UniProt: E1BKN2

Pathways: Regulation of Cell Size