tau antibody (AA 3-214)

Catalog No. ABIN1742569

This Rabbit Polyclonal antibody specifically detects tau in WB, IHC, ICC and IP. It exhibits reactivity toward Human, Mouse and Rat and has been mentioned in 2+ publications.

Quick Overview for tau antibody (AA 3-214) (ABIN1742569)

Target: tau (tau Protein)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This tau antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-tau Antibody

Binding Specificity: AA 3-214

Specificity: Specific for tau.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Recombinant mouse tau (aa 3-214).

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: 1 : 1000

Comment:

The antibody binds phosphorylated and non-phosphorylated tau proteins.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-tau antibody (ABIN1742569)

Schildknecht, Karreman, Pöltl, Efrémova, Kullmann, Gutbier, Krug, Scholz, Gerding, Leist: "Generation of genetically-modified human differentiated cells for toxicological tests and the study of neurodegenerative diseases." in: ALTEX, Vol. 30, Issue 4, pp. 427-44, (2013) (PubMed).

Tong, Wong, Guttman, Ang, Forno, Shimadzu, Rajput, Muenter, Kish, Hornykiewicz, Furukawa: "Brain alpha-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation." in: Brain : a journal of neurology, Vol. 133, Issue Pt 1, pp. 172-88, (2010) (PubMed).

Target Details for tau

Target: tau (tau Protein)

Alternative Name: tau