Interleukin 17a antibody

Catalog No. ABIN181032

The Rat Monoclonal anti-Interleukin 17a antibody (Clone TC11-8H4) (ABIN181032) specifically detects Interleukin 17a in EIA. The antibody is reactive with Mouse samples.

Quick Overview for Interleukin 17a antibody (ABIN181032)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Interleukin 17a antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: TC11-8H4

Product Details anti-Interleukin 17a Antibody

Specificity: This antibody recognises mouse Interleukin 17.

Characteristics: Synonyms: IL-17A, IL17, IL-17, CTLA8, CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8

Purification: Purified

Immunogen: Recombinant mouse IL-17 expressed in E. coli

Isotype: IgG1

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Borate buffered saline, pH 8.2

Storage: -20 °C

Storage Comment: Store the antibody in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: Interleukin-17A (IL17A)

Background: Interleukin 17 is a 32 kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17

Gene ID: 16171

UniProt: Q62386